DNA Nucleotidylexotransferase

A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catalyzes the elongation of oligo- or polydeoxynucleotide chains and is widely used as a tool in the differential diagnosis of acute leukemias in man. EC 2.7.7.31.

Also Known As:

Terminal Deoxynucleotidyl Transferase; Deoxynucleotidyl Transferase; Deoxynucleotidyltransferase; Desoxynucleotidyl Transferase; Desoxynucleotidyltransferase; Tdt Antigen; Terminal Deoxyribonucleotidyl Transferase; Addition Enzyme, Terminal; Antigen, Tdt; Deoxynucleotidyl Transferase, Terminal; Deoxyribonucleotidyl Transferase, Terminal; Deoxyribonucleotidyltransferase, Terminal; Enzyme, Terminal Addition; Nucleotidylexotransferase, DNA; Transferase, Deoxynucleotidyl; Transferase, Desoxynucleotidyl; Transferase, Terminal Deoxynucleotidyl; Transferase, Terminal Deoxyribonucleotidyl; Terminal Addition Enzyme; Terminal Deoxyribonucleotidyltransferase; Nucleoside-triphosphate:DNA deoxynucleotidylexotransferase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Nucleotidyltransferases: 29
        DNA Nucleotidyltransferases: 4
        DNA Nucleotidylexotransferase: 2269

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Disease

Drug/Important Bio-Agent (IBA)